ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Acyl-CoA desaturase 1

Intramolecular
Cysteine 92 and cysteine 97
A redox-regulated disulphide may form within Acyl-CoA desaturase 1 between cysteines 92 and 97.

Details

Redox score ?
69
PDB code
6wf2
Structure name
crystal structure of mouse scd1 with a diiron center
Structure deposition date
2020-04-03
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
26
Peptide accession
P13516
Residue number A
92
Residue number B
97
Peptide name
Acyl-CoA desaturase 1

Ligandability

Cysteine 92 of Acyl-CoA desaturase 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 97 of Acyl-CoA desaturase 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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